According to an international team of researchers, engineered bacteria could become potent allies in the battle against cancer.
Scientists have devised a method whereby a specific bacterium could identify the presence of colorectal cancer by detecting unique DNA sequences released by cancer cells. While the technique is still in the research stage and needs further testing for safety and effectiveness, utilizing modified microbes as diagnostic tools is gaining ground. Since our gastrointestinal system already hosts various bacteria, scientists have been striving to harness certain strains’ natural abilities as biosensors, showcasing promise in monitoring gut health and identifying ailments like intestinal bleeding, infections, and tumors.
The system’s sensitivity will determine its clinical usefulness, potentially enabling early bowel cancer detection. Comparisons with invasive techniques like colonoscopy will also be essential, especially as rates of bowel cancer rise in younger individuals who are typically not covered by cancer screening programs.